NMR analyses on N-hydroxymethylated nucleobases - implications for formaldehyde toxicity and nucleic acid demethylases

Org. Biomol. Chem., 2018, 16,4021-4032DOI: 10.1039/C8OB00734A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.S. Shishodia, D. Zhang, A. H. El-Sagheer, T. Brown, T. D. W. Claridge, C. J. Schofield, R. J. HopkinsonNMR studies reveal that formaldehyde, a toxic pollutant and metabolite, reacts with nucleotides to form N-hydroxymethylated adducts of varying stabilities.The content of this RSS Feed (c) The Royal Society of Chemistry

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