Government opens dynamic purchasing system procurement for HSCN

The RM3825 Health and Social Care Network Access Services dynamic purchasing system procurement has been opened to supplier bids

Government opens dynamic purchasing system procurement for HSCN

The RM3825 Health and Social Care Network Access Services dynamic purchasing system procurement has been opened to supplier bids

Government opens dynamic purchasing system procurement for HSCN

The RM3825 Health and Social Care Network Access Services dynamic purchasing system procurement has been opened to supplier bids

Openreach to open ‘grey’ fibre to broadband providers

Openreach is proposing to add a new feature to its optical spectrum access product to give broadband communication services providers more control over their networks

Openreach to open ‘grey’ fibre to broadband providers

Openreach is proposing to add a new feature to its optical spectrum access product to give broadband communication services providers more control over their networks

Openreach to open ‘grey’ fibre to broadband providers

Openreach is proposing to add a new feature to its optical spectrum access product to give broadband communication services providers more control over their networks

Openreach to open ‘grey’ fibre to broadband providers

Openreach is proposing to add a new feature to its optical spectrum access product to give broadband communication services providers more control over their networks

NFL tight end joins a company using VR to diagnose concussion

The evidence of traumatic brain injury is overwhelming. The league is hoping technology can help.

iOS tip: The handy shortcut menu hidden on your iPhone or iPad

Here's a simple trick that will make it much easier for you to find and use the buried features that you regularly use on your iPhone or iPad.

Today's Deal: Bosch 12V Cordless Drills Are on Sale

Get a great brushless drill/driver kit for $100.

British Medical Journal CDO on using Amazon and Alibaba for its multi-cloud strategy

A year on from embracing DevOps and private cloud to help speed up its software development lifecycle, British Medical Journal CDO Sharon Cooper shares an update on how its multi-cloud move is going

British Medical Journal CDO on using Amazon and Alibaba for its multi-cloud strategy

A year on from embracing DevOps and private cloud to help speed up its software development lifecycle, British Medical Journal CDO Sharon Cooper shares an update on how its multi-cloud move is going

British Medical Journal CDO on using Amazon and Alibaba for its multi-cloud strategy

A year on from embracing DevOps and private cloud to help speed up its software development lifecycle, British Medical Journal CDO Sharon Cooper shares an update on how its multi-cloud move is going

Nuclear Waste Dump in New Mexico Is Getting More Space

The work to carve out more disposal space will begin later this fall.

Adobe revamps Lightroom in major Creative Cloud update

Adobe unveiled a bevy of Creative Cloud updates at the Adobe MAX conference in Las Vegas.

Xbox One update: What does it feature and how do I install it?

The latest Xbox software update is now available to download. Here, we talk a little bit about what the latest Xbox One update offers, and how to install it on your Xbox One.

HP launches ZBook X2, claims it's "world's most powerful detachable PC"

The 14-inch mobile workstation is being introduced at Adobe's Max conference, and its top-notch specs and high price tag put it clearly in the same market as Microsoft's new Surface Book 2.

AppDynamics announces Business iQ updates, IoT and network visibility

The updates are all aimed at giving CIOs the tools to contribute more to strategic business decisions.

Trump denies 'insensitive' remarks to soldier's widow

The president says he has proof he did not make insensitive remarks to a slain soldier's wife.

FDA selects Box to help it modernize IT infrastructure

The deal is strategically important for Box as it grows its business in both the government and life sciences sectors.

Perfluorinated HDAC inhibitors as Selective Anticancer Agents

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB02339A, PaperJames William Walton, Jasmine Mary Cross, Tina Riedel, Paul DysonA series of potent histone deacetylase inhibitors is presented that incorporate alkyl or perfluorinated alkyl chains. Several new compounds show greater in vitro antiproliferate activity than the clinically approved inhibitor,...The content of this RSS Feed (c) The Royal Society of Chemistry

Tricyclanos: conformationally constrained nucleoside analogues with a new heterotricycle obtained from the D-ribofuranose unit

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB02296D, PaperMate Kicsak, Attila Mandi, Szabolcs Varga, Mihaly Herczeg, Gyula Batta, Attila Benyei, Aniko Borbas, Pal HerczeghA novel type of nucleoside analogues in which the sugar part is replaced by a new tricycle, 3,7,10-trioxa-11-azatricyclo[5.3.1.05,11]undecane has been prepared by substrate-controlled asymmetric synthesis.

Cu(II)-promoted Tandem Decarboxylative Halogenation and Oxidative Diamination Reaction of 2-Aminopyridines with Alkynoic Acids for the Synthesis of 2-Haloimidazo[1,2-a]pyridines

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB02014G, PaperYun Liu, Wenhui Wang, Junwen Han, Jinwei Wei SunA copper-promoted cascade decarboxylative halogention and oxidative diamination reaction sequence of 2-aminopyridines with alkynoic acids has been developed for the synthesis of 2-haloimidazo[1,2-a]pyridines. In this reaction, two C-N bonds and...The content of this RSS Feed (c) The Royal Society of Chemistry

Transition metal-catalyzed C-H bond functionalization in multicomponent reactions: a tool toward molecular diversity

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB02011B, Review ArticleJie-Ping Wan, Lu Gan, Yunyun LiuTransition metal-catalyzed C-H bond functionalization has exhibited numerous applications in organic synthesis as a powerful type of bond transformation. In particular, the combination of C-H functionalization with other types of...The content of this RSS Feed (c) The Royal Society of Chemistry

Substituent effects on stereoselectivity of dihalocarbene reactions with cyclohexadiene and on the reactivity of bis-dihalocyclopropanes in electrophilic nitrations on route to pyrimidine N-oxides

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB02463K, PaperKseniya N Sedenkova, Elena B. Averina, Y K. Grishin, Julia V. Kolodjashnaja, Victor B. Rybakov, Tamara S Kuznetsova, Audrey Hughes, Gabriel dos Passos Gomes, Igor Alabugin, Nikolay S. ZefirovTricyclic bis-adducts of cyclohexa-1,4-diene with bromofluorocarbene and non-symmetric with both bromofluoro- and dichlorocarbenes were synthesised selectively.

Iron (III)-catalyzed chelation assisted remote C-H bond oxygenation of 8-amidoquinolines.

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB02159C, PaperChandrasekharam Malapaka, Vinayak Botla, Pilli NavyasreeIron catalyzed site selective and chelation assisted C-H functionalization in 8-amidoquinolines is achieved. The remote C5-benzoxylation with benzoyl peroxide produced a variety of potentially bioactive 8-arylcarboxamido-5-benzoyloxy quinoline derivatives.

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